Singulair (montelukast) is a leukotriene inhibitor indicated to treat asthma. Its anti-inflammatory effect is also useful in seasonal allergy treatment. Paradoxically, it can cause hives. I had a patient who took it for asthma and allergies, and then developed severe hives. She was treated with multiple antihistamines, steroids, and finally Xolair, all to no effect. After two years she still had hives. Then she inadvertently stopped taking montelukast and the hives disappeared. A literature search showed that, sure enough, montelukast can cause hives. It’s rare, because her whole care team was floored.
I was prescribed montelukast. I didnt take it after reading about the adverse side effects. I really think that everyone should research every drug that they are prescribed. Doctors are always updated on side effects
30 years ago I was at the doctor's for a script for Voltaren for pain relief after becoming immune to all over the counter pain killers. The doctor said "yes it is a good pain killer but if you are to take it long term we'll have to look at giving you another medicine to protect your stomach".
I'm forever grateful for that remark as that was the turning point for me to study alternative medicine. I've been a homeopath for 20 years after this modality cured the chronic pain.
The worst pharma ad I’ve ever seen was for Seroquel XR I remember many years back I was watching Fox News in the morning while I was getting ready for work. That’s when the commercial came on.
I went and brushed my teeth, used mouthwash, trimmed some wild beard hairs, then went into the kitchen to make my coffee, loaded the coffee maker, and went to go put on my shoes—the commercial was still going.
The entire time it was listing potential side effects.
It made me think of Happy Fun Ball from SNL—only this was a real medication ad.
Back then Seroquel XR was marketed for depression. But I tell you what, if you had even a few of the side effects that were listed, you’d definitely be depressed.
That commercial is the first time I heard of Tardive dyskinesia. I had to look it up to find out what it was. The commercial went on to say, “Tardive dyskinesia might begin when you start taking Seroquel XR, or it might begin when you stop taking Seroquel XR.”
Really?! Why the hell would anyone take something that might cause permanent nerve damage, and uncontrollable muscle movements in the face?
What I’ve noticed more recently is the “weakened immune response” warning for damn-near every pharma product out there.
Well the Seroquel XR commercial was from 2009, I believe. It was way before The COVID-19 Scare.
But yes, I wonder if some of the weakened immune response warnings are covering for the COVID-19 vaccines.
That's a great point, because they can say, "Here's a list of medications that might result in a weekend immune response." And it's going to be pretty much *everything* now. 🙄
Why would they take something that might cause permanent nerve damage... Because "might" means really really unlikely and if you're looking for a potential solution to psychosis, I'm willing to take that risk. It's a cost benefit analysis that we do every day. Heck... That glass of water could make you sick... Random Hyponatremia is a thing.
There's nearly a 1% lifetime chance of dying in a car crash... Far higher than your risk of nerve damage from Quetiapine. And you're taking Q to treat severe psychosis, your car is simply a lifestyle convenience. Yet you don't ask why people get into a car everyday when the outcomes are so terrible... That's the question you really should be asking, not scaremongering about meds. Side effects are a legitimate concern, and they require considered cost benefit risk analysis, which involves knowing the numerical likelihood of harm and benefit, and you haven't mentioned a single cost benefit analysis and explanation of why people think the benefit is worth the risk. And again, seriously, the question to ask is why the benefit of cars are worth the risk...
Comparing the potential danger to driving a car to an anti-psychotic medication is a strange way to go with the conversation. 🤔
My point is that people don’t really know the cost vs benefit—when the manufacturer lies about the product. With Seroquel (quetiapine) Tardive Dyskinesia is not rare, at least not rare enough for them to leave it out of the commercial. AstraZeneca then went on to suggest that Seroquel be used for off-label use.
*****
[2010] AstraZeneca LP and AstraZeneca Pharmaceuticals LP will pay $520 million to resolve allegations that AstraZeneca illegally marketed the anti-psychotic drug Seroquel for uses not approved as safe and effective by the Food and Drug Administration (FDA), the Departments of Justice and Health and Human Services’ Health Care Fraud Enforcement Action Team (HEAT) announced today. Such unapproved uses are also known as "off-label" uses because they are not included in the drug’s FDA approved product label.
AstraZeneca marketed Seroquel (quetiapine) illegally—to the tune of a half-billion dollar fine. Do you really think that doctors were looking at the trial data and saying, “Wait a minute here, this is really for severe psychosis.” No. They just prescribed it as the manufacturer recommended, they see the commercials too.
What about the COVID-19 vaccines? The FDA was literally trying to keep the trial data from being made public—literally working to make sure that informed consent couldn’t happen.
*****
A federal judge has ordered the U.S. Food and Drug Administration to publicly disclose more information underpinning its authorization of COVID-19 vaccines, after failing to persuade the court to end the public records lawsuit.
In a ruling, on Friday, U.S. District Judge Mark Pittman in Fort Worth, Texas, ordered the agency to produce its “emergency use authorization” file to a group of scientists who wanted to see licensing information that the FDA relied on to approve the Pfizer-BioNTech coronavirus vaccine.
“The COVID-19 pandemic is long passed and so has any legitimate reason for concealing from the American people the information relied upon by the government in approving the Pfizer vaccine,” wrote Pittman, appointed in 2019 by then-President Donald Trump.
The lawsuit, filed in late 2021, attracted attention after the FDA said it could take decades to process and disclose records to Public Health and Medical Professionals for Transparency, the group that brought the case.
How is one supposed to determine their relative risk, when the manufacturers—and government regulatory agencies are working to hide the information required for consent?
How did the FDA approve the vaccines for use, in mere months, then claim that it will take decades to publish the data—the same data that the FDA supposedly used to claim the vaccines were safe and effective with breathtaking speed?
I’m not saying that some medications don’t help some people. They must or nobody would take them.
In a zero-trust scenario, the FDA fails, they can’t make their case, and they’ve proven that. The FDA is not for transparency, which means that they are at least aiding in potential fraud—and at worst are directly involved in fraud.
My husband went deaf in one ear following his initial Covid vaccines. Blessedly it improved a year later and he had to change the hearing aid accordingly.
Another one that needs mentioning is hearing loss from Viagra, Cialis, etc. My husband’s doctor prescribed it but had no idea until it happened to my husband. Profound, irreversible for him. The ENT super-specialist we eventually saw was familiar with it. But of course, he’s not the doc prescribing it!
Would love for you to do research on nicotine and how it can help those suffering with pain, or other ailments. Also known to help with ADHD and other neurological symptoms.
Makes me never want to take another med.
Ah yes, then another pill for the side effect, then another for that side effect, and so on
Singulair (montelukast) is a leukotriene inhibitor indicated to treat asthma. Its anti-inflammatory effect is also useful in seasonal allergy treatment. Paradoxically, it can cause hives. I had a patient who took it for asthma and allergies, and then developed severe hives. She was treated with multiple antihistamines, steroids, and finally Xolair, all to no effect. After two years she still had hives. Then she inadvertently stopped taking montelukast and the hives disappeared. A literature search showed that, sure enough, montelukast can cause hives. It’s rare, because her whole care team was floored.
I was prescribed montelukast. I didnt take it after reading about the adverse side effects. I really think that everyone should research every drug that they are prescribed. Doctors are always updated on side effects
Here’s another bizarre side effect from the COVID shots:
https://substack.com/@laurakasner/note/c-139865232?
30 years ago I was at the doctor's for a script for Voltaren for pain relief after becoming immune to all over the counter pain killers. The doctor said "yes it is a good pain killer but if you are to take it long term we'll have to look at giving you another medicine to protect your stomach".
I'm forever grateful for that remark as that was the turning point for me to study alternative medicine. I've been a homeopath for 20 years after this modality cured the chronic pain.
The worst pharma ad I’ve ever seen was for Seroquel XR I remember many years back I was watching Fox News in the morning while I was getting ready for work. That’s when the commercial came on.
I went and brushed my teeth, used mouthwash, trimmed some wild beard hairs, then went into the kitchen to make my coffee, loaded the coffee maker, and went to go put on my shoes—the commercial was still going.
The entire time it was listing potential side effects.
It made me think of Happy Fun Ball from SNL—only this was a real medication ad.
Back then Seroquel XR was marketed for depression. But I tell you what, if you had even a few of the side effects that were listed, you’d definitely be depressed.
That commercial is the first time I heard of Tardive dyskinesia. I had to look it up to find out what it was. The commercial went on to say, “Tardive dyskinesia might begin when you start taking Seroquel XR, or it might begin when you stop taking Seroquel XR.”
Really?! Why the hell would anyone take something that might cause permanent nerve damage, and uncontrollable muscle movements in the face?
What I’ve noticed more recently is the “weakened immune response” warning for damn-near every pharma product out there.
Is it just me, or is that new?
https://www.youtube.com/watch?v=GmqeZl8OI2M
Probably true, but they may also be covering for Covid vaccines that have done the same to likely billions of people
Well the Seroquel XR commercial was from 2009, I believe. It was way before The COVID-19 Scare.
But yes, I wonder if some of the weakened immune response warnings are covering for the COVID-19 vaccines.
That's a great point, because they can say, "Here's a list of medications that might result in a weekend immune response." And it's going to be pretty much *everything* now. 🙄
Why would they take something that might cause permanent nerve damage... Because "might" means really really unlikely and if you're looking for a potential solution to psychosis, I'm willing to take that risk. It's a cost benefit analysis that we do every day. Heck... That glass of water could make you sick... Random Hyponatremia is a thing.
There's nearly a 1% lifetime chance of dying in a car crash... Far higher than your risk of nerve damage from Quetiapine. And you're taking Q to treat severe psychosis, your car is simply a lifestyle convenience. Yet you don't ask why people get into a car everyday when the outcomes are so terrible... That's the question you really should be asking, not scaremongering about meds. Side effects are a legitimate concern, and they require considered cost benefit risk analysis, which involves knowing the numerical likelihood of harm and benefit, and you haven't mentioned a single cost benefit analysis and explanation of why people think the benefit is worth the risk. And again, seriously, the question to ask is why the benefit of cars are worth the risk...
Comparing the potential danger to driving a car to an anti-psychotic medication is a strange way to go with the conversation. 🤔
My point is that people don’t really know the cost vs benefit—when the manufacturer lies about the product. With Seroquel (quetiapine) Tardive Dyskinesia is not rare, at least not rare enough for them to leave it out of the commercial. AstraZeneca then went on to suggest that Seroquel be used for off-label use.
*****
[2010] AstraZeneca LP and AstraZeneca Pharmaceuticals LP will pay $520 million to resolve allegations that AstraZeneca illegally marketed the anti-psychotic drug Seroquel for uses not approved as safe and effective by the Food and Drug Administration (FDA), the Departments of Justice and Health and Human Services’ Health Care Fraud Enforcement Action Team (HEAT) announced today. Such unapproved uses are also known as "off-label" uses because they are not included in the drug’s FDA approved product label.
*****
https://www.justice.gov/archives/opa/pr/pharmaceutical-giant-astrazeneca-pay-520-million-label-drug-marketing
AstraZeneca marketed Seroquel (quetiapine) illegally—to the tune of a half-billion dollar fine. Do you really think that doctors were looking at the trial data and saying, “Wait a minute here, this is really for severe psychosis.” No. They just prescribed it as the manufacturer recommended, they see the commercials too.
What about the COVID-19 vaccines? The FDA was literally trying to keep the trial data from being made public—literally working to make sure that informed consent couldn’t happen.
*****
A federal judge has ordered the U.S. Food and Drug Administration to publicly disclose more information underpinning its authorization of COVID-19 vaccines, after failing to persuade the court to end the public records lawsuit.
In a ruling, on Friday, U.S. District Judge Mark Pittman in Fort Worth, Texas, ordered the agency to produce its “emergency use authorization” file to a group of scientists who wanted to see licensing information that the FDA relied on to approve the Pfizer-BioNTech coronavirus vaccine.
“The COVID-19 pandemic is long passed and so has any legitimate reason for concealing from the American people the information relied upon by the government in approving the Pfizer vaccine,” wrote Pittman, appointed in 2019 by then-President Donald Trump.
The lawsuit, filed in late 2021, attracted attention after the FDA said it could take decades to process and disclose records to Public Health and Medical Professionals for Transparency, the group that brought the case.
The FDA declined to comment.
*****
https://nypost.com/2024/12/06/business/fda-must-disclose-more-covid-19-vaccine-records-us-judge-rules/
How is one supposed to determine their relative risk, when the manufacturers—and government regulatory agencies are working to hide the information required for consent?
How did the FDA approve the vaccines for use, in mere months, then claim that it will take decades to publish the data—the same data that the FDA supposedly used to claim the vaccines were safe and effective with breathtaking speed?
I’m not saying that some medications don’t help some people. They must or nobody would take them.
In a zero-trust scenario, the FDA fails, they can’t make their case, and they’ve proven that. The FDA is not for transparency, which means that they are at least aiding in potential fraud—and at worst are directly involved in fraud.
My husband went deaf in one ear following his initial Covid vaccines. Blessedly it improved a year later and he had to change the hearing aid accordingly.
Elevated blood sugar from Seroquel or statins.
how are ANY of us alive?
Depression or extreme emotional reaction can come from Singulair
That's an amazing summary Sharyl. Here's more on Antibiotics - Have you been Floxed?
https://theylied.substack.com/p/theylied-antibiotics-have-you-been
.
Another one that needs mentioning is hearing loss from Viagra, Cialis, etc. My husband’s doctor prescribed it but had no idea until it happened to my husband. Profound, irreversible for him. The ENT super-specialist we eventually saw was familiar with it. But of course, he’s not the doc prescribing it!
I call these ‘effects’- not ‘side effects’. They were meant to be how they are.
Great article. Everyone should read this.
"There are no side effects; there are only effects." --Dr. Kelly Brogan
Also, ma'am, you forgot to mention Akathisia, which affects 30-40% of those who have taken an "antipsychotic" drug.
Would love for you to do research on nicotine and how it can help those suffering with pain, or other ailments. Also known to help with ADHD and other neurological symptoms.
I was jazzed to try nicotine but noticed it seemed to affect my arrhythmia ( worse) so I stopped
I think the good and the bad need to be looked at! What were you using it for?